Post 5: Chances of passing on hemophilia

Hemophilia is easily spread from parents to offspring. There are five possible scenarios in which a child can receive hemophilia from his or her parents:

  • affected dad + unaffected mom (Square 1)
  • affected dad + carrier mom (Square 2)
  • affected dad + affected mom (Square 3)
  • normal dad + carrier mom (Square 4)
  • normal dad + affected mom (Square 5)

Here are the corresponding Punnett Squares:

  • Square 1: 0% of children will be hemophilic. However, 100% of daughters will be carriers.
  • Square 2: 50% of children will be hemophilic. 50% of daughters will be hemophilic, 50% will be carriers. 50% of males will be hemophilic, 50% will not.

  • Square 3: 100% of children will be hemophilic.
  • Square 4: 25% of children will be hemophilic. 50% of girls will be carriers, 50% will not be affected. 50% of males will be hemophilic, 50% will not.

  • Square 5: 50% of children will be hemophilic. 100% of girls will be carriers, 100% of males will be hemophilic.

These are all the possible ways that children can inherit hemophilia from their parents. I hope this post wasn’t too difficult to follow. ;)

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